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Staff Scientist/Leader, Integrated Mouse Modelling Services (IMMS) - BC Cancer, Vancouver

Staff Scientist/Leader, Integrated Mouse Modelling Services (IMMS)
Terry Fox Laboratories,

BC Cancer Vancouver


As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.


Reporting to the Scientific Director, BC Cancer Animal Resource Centre, the Leader, Integrated Mouse Modelling Services (IMMS) will be responsible for the operation and expansion of a mouse genetic modelling core for BC Cancer and the University of British Columbia. The IMMS will evolve from the current Genetic Modelling Core located at BC Cancer Research Institute (BCCRI). The Leader will have oversight of all services offered by the IMMS, while also evaluating and implementing new emerging mouse genetic modification technologies to provide scientific support and services to BC Cancer, UBC and other external research teams on fee for service basis. The Leader will also be expected to develop a strategic plan for growth of the IMMS while also acting as a mentor for other IMMS research personnel. The Leader must be passionate about mouse genetics models and mouse pluripotent stem cells and their application to disease models while also having an appreciation for building collaborative relationships with diverse groups with mouse modelling needs. Furthermore, this position involves insights into scientific structures, processes of relevant research alliances, a high degree of creativity, interdisciplinary and transdisciplinary thinking.


The Leader, IMMS will provide a vision for the implementation of a successful IMMS at the BC Cancer Research Institute, responsibilities include:


Establishment and Provision of the following services based on fee for service model:

  • Generation of new mouse models: Assisting researchers with experimental design to determine the best approach to meet their needs. Services include embryonic stem cell modification and, zygote and embryo injections. CRISPR-Cas9 methods and standard methods are used.
  • Cryopreservation and Rederivation of mouse lines: Cryopreservation of mouse sperm and embryos for long term storage and, IVF and embryo transfer methods for recovery and rederivation.


Scientific Support and Collaboration:

  • Write letters and provide quotations as support in grant applications for researchers planning to use the core.
  • Fully document research work and assist researchers in the preparation of manuscripts by providing experimental details.
  • Collaborate with other cores at UBC to provide continuity in services for research projects.


Management and Finance:

  • Manage the core facility and its staff, including recruitment, retention and termination.
  • Present core services to potential users inside and outside UBC; establish contacts in and outside BCCRI to raise the profile of the IMMS; develop a communication (via seminars, emails and social media platform) and advertising plan for IMMS core services.
  • Report to the Scientific Director, Animal Resource Centre on the current use and potential needs for growth and diversification of the core.
  • Provide financial evaluation of new projects, technologies and operation of the core; develops funding models for sustainment
  • Prepare budgets and develop efficient tools for billing and accounting of fee for service model
  • Track deliverables for IMMS projects to ensure success of core
  • Collaborate with the Operations Manager, Animal Resource Centre around staffing and provision of specialized services


What you bring

  • PhD in Genetics, Molecular Biology or related discipline.
  • Seven (7) years relevant experience or equivalent combination of education and experience.


You Have

  • Demonstrated experience in genome engineering and mouse genetic models,
  • Knowledge of generating budgets and costing structures for various services offered by the core.
  • Established knowledge of laboratory safety plans and procedures to ensure compliance with applicable federal, provincial and local regulations.
  • Effective oral, written, interpersonal, analytical, organizational skills and scheduling abilities.
  • Demonstrated integrity, credibility, and a positive attitude.
  • Experience in developing and implementing standard operating procedures.
  • Strong English communications skills (verbal and written).
  • Ability to convey concepts and analysis results to non-specialists.
  • Self-directed, self-motivated and independent research skills.
  • Ability to mentor and direct junior staff and trainees.
  • Develop, prioritize and implement multiple time-sensitive research projects.
  • A strong publication record is a definite asset.


What we bring

Every PHSA employee enables the best possible patient care for our patients and their families. Whether you are providing direct care, conducting research, or making it possible for others to do their work, you impact the lives of British Columbians today and in the future. That’s why we’re focused on your care too – offering health, wellness, development programs to support you – at work and at home.

  • Join one of BC’s largest employers with province-wide programs, services and operations – offering vast opportunities for growth and development.
  • Access to professional development opportunities through our in-house training programs, including +2,000 courses, such as our San’yas Indigenous Cultural Safety Training course, or Core Linx for Leadership roles.
  • Enjoy a comprehensive benefits package, including municipal pension plan, and psychological health & safety programs and holistic wellness resources.
  • Annual statutory holidays (13) with generous vacation entitlement and accruement.
  • PHSA is a remote work friendly employer, welcoming flexible work options to support our people (eligibility may vary, depending on position).
  • Perks include access to fitness classes and discounts to 350 BC-wide recreational programs, travel, technology, car and bike sharing, and more.


Temporary, Full-Time (1 Year Term)
675 West 10th Avenue, Vancouver BC, V5Z 1L3
Applications will be accepted until position is filled.
Monday to Friday; 0930-1730
Requisition Number: 110914


What we do


BC Cancer provides comprehensive cancer control for the people of British Columbia.


The Provincial Health Services Authority (PHSA) plans, manages and evaluates specialized health services with the BC health authorities to provide equitable and cost-effective health care for people throughout the province. Our values reflect our commitment to excellence and include: Respect people – Be compassionate – Dare to innovate – Cultivate partnerships – Serve with purpose.


Learn more about PHSA and our programs:


PHSA and BC Cancer are committed to employment equity, encouraging all qualified individuals to apply. We recognize that our ability to provide the best care for our diverse patient populations relies on a rich diversity of skills, knowledge, background and experience, and value a safe, inclusive and welcoming environment.